SONGKLANAKARIN JOURNAL OF SCIENCE & TECHNOLOGY

Volume 42, No. 05, Month SEPTEMBER, Year 2020, Pages 1091 - 1097

Bioactivities of selected herbs in relation to the body elements in traditional thai medicine

Boontarika Yudee , Wudtichai Wisuitiprot , Siwames Netsopa and Neti Waranuch

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Thai Traditional Medicine believes that human body is composed of four elements. It also mentions that skin problems related to each element can be alleviated by using suitable plants. This study aimed to determine the bioactivities related to skin effects of Aloe vera, Cucumis sativus, Alpinia galanga and Phyllanthus emblica. The plants were extracted with 50% ethanol prior to bioactivity evaluation. The highest anti-oxidant activity (IC50, 14.01 μg/ml) was found for P. emblica. Tyrosinase inhibition was found with P. emblica (41.92% inhibition) and A. vera (26.67% inhibition) at 500 μg/ml concentrations. The cells treated with 500 μg/ml A. vera and 15.62 μg/ml P. emblica had after 48 h increased collagen type-1 production by around 14 and 4 -fold from those of untreated cells. Anti-glycation was found with P. emblica. P. emblica, A. galanga and C. sativus at 62.5 μg/ml exhibited anti-inflammatory activity. This information supports evidence based use of these plants as food and cosmetic ingredients.

Keywords

Thai Traditional Medicine, anti-aging, anti-oxidant, anti-glycation, collagen synthesis

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