Antimicrobial resistance (AMR) is critical situation for human and animal health worldwide. The
inappropriate antimicrobial use is one of the risk factors of AMR. Intriguingly, an increase of antimicrobial
resistance bacteria was recently evident in companion animals. Since such circumstance strongly implied the
contribution of inappropriate antimicrobial use in veterinary clinics and hospitals to the problems, this study
aimed to categorize and evaluate antimicrobials prescribed in the Veterinary Teaching Hospital in Thailand.
From 6,200 animal patients, there were total 8,093 antimicrobial prescriptions for animal treatments.
The antimicrobials were prescribed for parenteral administrations 3,346 prescriptions (41.3%) and oral
administrations 4,747 prescriptions (58.7%), respectively. During 2012-2015, the most antimicrobial prescriptions
were enrofloxacin (33.9%, P<0.001) with significantly difference from amoxicillin/clavulanate (24.1%) and
doxycycline (15.2%). Enrofloxacin was highest prescribed in both parenteral and oral administrations (41.2% and
28.8%, respectively). Surgical procedure was topmost of parenteral antimicrobial prescriptions (16.5%, P<0.05),
especially for neutering cases, followed with gastrointestinal system (14.6%) and dermatological system (9.5%).
The most oral antimicrobial prescriptions were used for treatments of dermatological system (16.3%,
P<0.05), gastro-intestinal system (11.1%) and surgical procedures (8.9%). These study revealed the pattern of
antimicrobial use in companion animals to fulfill the associated picture with AMR problem in Thailand, and
underline requirement of better solving plan based on one health approach with more concern of antimicrobial
use in veterinary fields.