A 12-year-old spayed female poodle dog had clinical sign of stranguria. The dog was definitive diagnosed
by radiography, ultrasonography and histopathology that it was invasive transitional cell carcinoma at the neck
of urinary bladder. The dog was treated with meloxicam and black sesamin. The side effects of treatment,
blood profiles and urinalysis were investigated once a month and urinary bladder ultrasonographic examination
was performed every two months for disease progression monitoring. The dog had the stable size of mass. The
side effects of meloxicam were not observed during treatment.